In Vitro Antioxidant and Sunscreen Activities of Gyrinops versteegi Leaf Extract from Different Location in Indonesia and Phytosome Combinations-Reference-Cited by-同舟云学术

In Vitro Antioxidant and Sunscreen Activities of Gyrinops versteegi Leaf Extract from Different Location in Indonesia and Phytosome Combinations

Published:2022-11-24 Issue: Volume: Page:5106-5111
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Kartika Sari Rita¹,Wahyuningrum Maeda²,Arib Rozan Salman²,Aulia M. Ilham²,Rafi Mohamad³,Wientarsih Ietje⁴

Affiliation:

1. Tropical Biopharmaca Research Center, IPB University, Bogor 16128, Indonesia.

2. Department of Forest Products, Faculty of Forestry and Environment, IPB University, Bogor 16680, Indonesia.

3. Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor 16680, Indonesia.

4. Department of Clinic, Reproduction, and Pathology, IPB University, Bogor 16680, Indonesia.

Abstract

This study aimed to determine antioxidant activity (AA), sunscreen activity (SA), and phytochemical profiles of G. versteegii leaf extracts from West Java (WJ) and Central Java (CJ) and its phytosome. The samples were extracted using the maceration method with 50% ethanol (E50). The AA of extracts was evaluated using in vitro assay with the 2,2-diphenyl-l-picrylhydrazyl (DPPH) and cupric reducing antioxidant capacity (CUPRAC) methods. The SA of extracts was expressed as a sun protection factor (SPF). The result showed that the E50 extract from WJ was the higher of yield, AA, SPF, and total phenolic content (TPC) about 25.4%, 38.92 μmol-trolox/g (DPPH) and 768.93 μmol-trolox/g (CUPRAC), 14.84 (classified as maximum), and 77.01 mg gallic acid equivalent (GAE)/g sample, respectively. The phytosome formulas were made with different ratios of E50 extract and soy lecithin of F1 (1:2), F2 (1:1), and F3 (2:1). The best phytosome formula was the F2 (ratio of extract: lecithin was 1:1) with the yield, AA, SPF, and TPC was 85.47%, 1535.1 μmol-trolox/g (CUPRAC), 13.74 (classified as maximum), and 174 mg GAE/g, respectively. TPC of the extract and phytosome was positively correlated with AA.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference38 articles.

1. Susmianto A, Turjaman M, Setio P. Track Record of Inoculation Agarwood. FORDA Press, Bogor. 2014.

2. Central Bureau of Statistics. Bulletin of foreign trade export statistics based on a harmonized system of December 2019. PT Citra Mawana Patamoro Jakarta, Jakarta. 2019.

3. Barden A, Anak NA, Mulliken T, Song M. Heart of the matter: agarwood use and trade and cites implementation for Aquilaria malaccensis. Traffic Network Report: Cambridge. 2000.

4. Santoso E, Turjaman M, Irianto RSB, Agustini L, Efiyanti L, Faulina SA. Forestry science and technology book series V. Puslitbang Bogor: Bogor. 2014.

5. Wahyuningrum M, Sari RK, Rafi M. Antioxidant activity and sunscreen of Gyrinops versteegii leaf extract. Jurnal Ilmu dan Teknologi Kayu Tropis. 2018 July 2;16(2):141-149.