Affiliation:
1. Clinical Communicable Diseases Research Unit, College of Medicine, University of Baghdad, Iraq.
2. Central Public Health Laboratories in Baghdad Province.
Abstract
Background: Recently it has been noticed that toxoplasmosis played an important role in distressing women’s pregnancy through certain outcomes such as congenital abnormalities and abortions. The lack in Vitamin D may play role fragility of bones like; osteoporosis, and bone deformities. Objective: To evaluate the association between the lake in vitamin D and toxoplasmosis seropositivity in the women’s sera in the age of childbearing by applying ELISA method. Materials and Methods: 56 women, from Central Public Health Laboratories in Baghdad Province were selected in this study, their age range between (17-45) years. The individuals were diagnosed with BOH (Bad Obstetric History). Among 56 women infected (44)or not infected (12)with toxoplasmosis blood samples were collected from patients who visited Central Public Health Laboratories in Baghdad Province . IgG and IgM Abs Antibodies against Toxoplasma gondii were detected using minividas kit ) BioMerieux /France). Also vitamin D was detected using by ELISA microwells method (Monobind Inc. USA). Results: The results were considered as statistically significant (P=0.386), it shows no important difference between toxoplasmosis and the concentration of vitamin D3 in women with history of abortion or not. Conclusion: The toxoplasmosis rate in women in childbearing age was elevated, and the association between vitamin D deficiency and toxoplasmosis was not considerable.
Subject
Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)