Qualitative Phytochemical Screening and Antifungal Activity of Ethanol Extract of Young Papaya Seeds (Carica papaya L.) against Candida albicans

Abstract

The object of this study was aimed to determine the antifungal activity of papaya seeds (Carica papaya L.) ethanol extract against the fungi Candida albicans. The research method was experimental research consisting of several stages of sample processing, extraction, phytochemical screening, and tested antifungal activity of ethanol extract of papaya seeds young. Screening of Phytochemical results showed that ethanol extract of papaya seeds contains flavonoids, alkaloids, tannins, steroids and saponins. Test antifungal activity carried out by the agar diffusion method (pitting) was by measuring the inhibition zone formed around the wells. The test results showed that the antifungal activity of ethanol extract of papaya seeds had antifungal activity against Candida albicans at 0.1%, 0.3%, 0.6% and 1% in diameter inhibition zone respectively by 11mm; 12mm; 13mm; and 14 mm and are included in the category of strong inhibition.