Simultaneous Estimation of Ketorolac Tromethamine and Ofloxacin-Reference-Cited by-同舟云学术

Simultaneous Estimation of Ketorolac Tromethamine and Ofloxacin

Published:2022-06-28 Issue: Volume: Page:2498-2502
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Hashim Mansoori Mohammad¹,Sahu Bharat²,Shah Kamal³

Affiliation:

1. M. S. College of Pharmacy Devghar Taq-Wada District-Palghar Maharashtra India.

2. Adina Institute of Pharmaceutical Sciences, Sagar, Madhya Pradesh, India.

3. Institute of Pharmaceutical Research, GLA University, 17 Km Stone, NH-2, Mathura-Delhi Road, P.O. Chaumuhan, Mathura - 281406 (U.P.), India.

Abstract

A cost-effective and simple spectrophotometric technique is established for the quantification of Ofloxacin and Ketorolac tromethamine in bulk drug and eye drops. In the present case the method developed based on simultaneous equation method. The two wavelengths were selected that is 296 nm and 320 nm. The equation was designed and the absorption coefficients for both of the drugs at both the wavelength was calculated. The developed method was applied to formulations too. Analysis of results were statistically validated and by resurgence studies. For routine determination of Ofloxacin and Ketorolac tromethamine, the method was found to be suitable in bulk drug and in formulations. Therefore, the current work aims in developing an easy method for spectrophotometric determination of Ofloxacin and Ketorolac tromethamine in eye drop dose form.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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