Hypolipidemic Effect of The Fruit Juice of Hippophae rhamnoides L. (Seabuckthorn) in Hypercholesteremic New Zealand Rabbits Model-Reference-Cited by-同舟云学术

Hypolipidemic Effect of The Fruit Juice of Hippophae rhamnoides L. (Seabuckthorn) in Hypercholesteremic New Zealand Rabbits Model

Published:2022-06-28 Issue: Volume: Page:2565-2570
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Praharaj Shuvranshu¹,Kalaichelvan V. K.²,Murugan V.²,Ahmad Ishtiyaque³,Kumar Giri Ranjan⁴

Affiliation:

1. Annamalai University, Annamalai Nagar, Tamilnadu, India.

2. College of Pharmaceutical Sciences, Dayananda Sagar University, Bangalore, India.

3. Jubilant Biosys, Bangalore.

4. Institute of Pharmacy and Technology, Salipur, Cuttack, Odisha, India.

Abstract

Hypolipidemic effect of fruit juice of Hippophae rhamnoides L was evaluated in 1% cholesterol and 10% ground nut oil diet induced hyper cholesteremic models of New Zealand rabbits. The fruit juice at 0.46ml/kg body weight reduced the elevated serum total cholesterol (TC), triglyceride, low density cholesterol (LDL-C), atherogenic index, and C - reactive protein levels on diet induced rabbits. The juice at the same dose significantly enhanced the high density lipoprotein (HDL) in high fat diet (HFD) induced hyperlipidemic rabbits. The reference compound atorvastatin showed significant (p<0.05) effects.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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