Levels of Lipids Associated with Sialic Acids in Sera of Leukemic and Hodgkin’s patients

Author:

Sami Kadhim Mohammed1,A. Mohamed Khalil Ismail2,T. Al-Karkhi Isam Hussain3

Affiliation:

1. Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq.

2. Clinical Communicable Diseases Research, College of Medicine, University of Baghdad, Iraq.

3. Former Assistant Prof. University of Baghdad, Iraq.

Abstract

Total Sialic Acid (TSA), Lipid Associated Sialic Acid (LASA), Total Protein (TP), and (TSA/TP) ratio values were determined in sera of 152 leukemic patients, 26 Hodgkin’s patients, 37 patients with non-cancer disease as (a pathological control) and 12 normal healthy individuals. Results analysis revealed a significant (P<0.001) increases in the mean (±SD) of (TSA) and (TSA/TP) values in sera of leukemia, Hodgkin’s patients compared with pathological control and normal healthy individuals. A moderated increase in the total protein (TP), values in all types of leukemia and Hodgkin’s patients compare with normal healthy (control). A significant increase in (LASA) (P<0.001) values in all types of leukemic and Hodgkin’s patients compared with pathological control of normal healthy individuals.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference15 articles.

1. Kumar K, Jain P, Sinha A, Singh KK, Sharma HP. Clinical Significance of Tumour Markers. American Journal of Phytomedicine and Clinical Therapeutics. 2014; 2(8): 1005-1015

2. Sreeramulu V, Ramana V. Evaluation of Serum Total and Lipid Associated Sialic Acid as a Tumor Marker in Breast Malignancy. Journal of Pharmacy and Biological Sciences. 2014; 9(2): 14-17

3. Durgawale P, Sontakke A, Shukla PS, Durgawale P, Chougule P. Alterations in Total Sialic Acid (TSA), Total Proteins (TP) and TSA/TP ratio in cancer patients. Biomedical Research. 2011; 22 (4): 492-494

4. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. Biological Chemistry. 1951; 193: 265-275.

5. Katopodis N, Y Hirshaut Y, Geller NL, Stock CC. Lipid-associated Sialic Acid Test for the Detection of Human Cancer. Cancer Res. 1982; 42(12): 5270-5275.

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