Bridging between disorder, prevalence, clinical manifestation and therapeutic management of muscular dystrophy

Author:

Chandra Sattenapalli Nigama1,Prasad Swain Ranjit2,Koteswara Rao Gudhanti Siva Naga1

Affiliation:

1. Department of Pharmaceutics, K L College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, A.P., India.

2. Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.

Abstract

The main purpose of the present review is to compile the recent information with special focus on different aspects of muscular dystrophy. Muscular dystrophies are the group of genetic disorders that causes progressive muscle weakness and degeneration of skeletal muscles, restricts their movement and functions, and is irreversible. There is no clear picture and statistics on muscular dystrophy effected individuals especially in India. This article specifies and acknowledges the muscular dystrophy facts and particulars all over the world especially focusing the story in India. The study is based on statistics taken from several reports gathered by different organizations in India, as well as, from other data sources published. In this regard, this present review highlighted the areas of epidemiology, present scenario of prevalence, types of muscular dystrophy specially focused on genetic involment, identification of clinical symptoms, clinical diagnosis specially focused in India, care, management and treatment of this disorder.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference49 articles.

1. Muscular dystrophy information page. Available on http://www.ninds.nih.gov/disorders/md/md.htm accessed on 24.04.2020.

2. Nigro G. One-hundred-seventy-five years of Neapolitan contributions to the fight against the muscular diseases. Acta Myologica. 2010; 29: 369-391.

3. Conte G, Gioja L. Scrofola del sistema muscolare. Annali Clinici dell'Ospedale degli Incurabili di Napoli 1836; 2:66-79.

4. Semmola G. Sopra due malattie. Notiziedell’atrainfermita, AcadPontaniana.1834:164-165.

5. Meryon E. On granular and fatty degeneration of the voluntary muscles. Medico-Chirurgical Transactions.1852; 35:73-74.

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