Apium graveolens L.: A Phytochemical and Pharmacological Review-Reference-Cited by-同舟云学术

Apium graveolens L.: A Phytochemical and Pharmacological Review

Published:2022-02-26 Issue: Volume: Page:927-934
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

E.I. Makarova¹,D.O. Bokov¹,E.V. Sergunova¹,V.V. Chevidaev¹,S.D. Kakhramanova²,V.V. Bessonov³,N.V. Friesen⁴,A.N. Luferov¹

Affiliation:

1. Sechenov First Moscow State Medical University, 8 Trubetskaya St., Bldg. 2, Moscow, 119991, Russian Federation.

2. Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products”, 8/2 Petrovsky Boulevard, Moscow, 127051, Russian Federation.

3. Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, Russian Federation.

4. Botanical Garden of the University of Osnabrueck, Albrechtstr. 29, Osnabrueck, 490776 Germany.

Abstract

Phytochemical composition data of various parts of celery (Apium graveolens L.) and pharmacological activity thereof are analyzed herein. Flavonoids, organic acids, hydroxycinnamic acids, ether oil terpenoids, tannins, vitamins and microelements are A. graveolens biologically active substances (BAS). Rich composition of BAS causes multiple both biological and pharmacological effects of herbal raw materials extracts mainly due to antioxidant activity. Furthermore, the extracts have neuroprotective, anti-inflammatory, hypolipidemic, antihypertensive and antibacterial effects. A. graveolens possesses wide spectrum of pharmacological activities and is a nontoxic plant; A. graveolens-based medicines will have high margin of safety. The results obtained provide opportunities for making herbal pharmaceutical celery-based substances and introduction thereof into the academic medicine.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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