Author:
Novikov Vasiliy Egorovich,Levchenkova Olga Sergeevna,Pozhilova Yelena Vasilyevna
Abstract
This review is devoted to analysis of modern scientific investigations about role of reactive oxygen species (ROS) in physiology and pathophysiology of cell. Key issues of ROS generation, their function in signaling pathways, role in the cellular pathology, functioning of antioxidant system are discussed in the paper. The review also summarizes literature data about possibility of pharmacological regulation of the activity of free radical oxidation reactions, which have practical value for effective pharmacotherapy of diseases in pathogenesis of which destructive action of ROS is present.
Cited by
19 articles.
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