COMPARISON OF EFFICACY AND TOLERANCE OF THE INTRAPERITONEAL CELL-BASED AND IL-2 IMMUNOTHERAPY OF PATIENTS WITH CHEMOTHERAPY-RESISTANT GASTRIC CANCER AND MALIGNANT ASCITES-Reference-Cited by-同舟云学术

COMPARISON OF EFFICACY AND TOLERANCE OF THE INTRAPERITONEAL CELL-BASED AND IL-2 IMMUNOTHERAPY OF PATIENTS WITH CHEMOTHERAPY-RESISTANT GASTRIC CANCER AND MALIGNANT ASCITES

Published:2014-06-15 Issue:3 Volume:19 Page:24-28
ISSN:2412-9119
Container-title:Russian Journal of Oncology
language:
Short-container-title:Russian Journal of Oncology

Author:

Titov K. S,Demidov L. V,Shubina I. Zh,Kiselevsky M. V

Abstract

Most often gastric cancer is accompanied with abdominal carcinomatosis tumor (metastases) ascites (25 %), which is a life-threatening complications of tumor process, often recurring after systemic drug therapy which not always leads to a longer remission, but is also accompanied by severe side effects. Intraperitoneal immunotherapy of metastatic ascites interleukin-2 (IL-2) in combination with allogeneic (donor) lymphokine - activated killer (LAK) and IL-2 monotherapy is highly effective and well tolerated in patients with gastric cancer. Objective effect of the treatment was 50.0 % and 42.8 %, respectively. Proposed form of immunotherapy can be considered as one of the stages combined drug treatment, has good tolerance and improves their quality of life.

Publisher

ECO-Vector LLC

Subject

General Medicine

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