Normal concentration of oral fluid procalcitonin and concentration in periodontitis

Abstract

Objective. To study the procalcitonin concentration (PCC) in the oral fluid of healthy persons and patients with periodontitis. Materials and methods. The procalcitonin concentration was studied in the oral cavity of 42 patients with periodontitis (main group) and 25 patients with sanitized oral cavity (comparison group). Results. The result medians in the comparison group by 1.658 times exceeded the median in the main group (р = 0,004315) and made up for the main group 114 (64; 144) pg/ml and for the comparison group 189 (117; 485) pg/ml. No differences in the oral fluid PCC concentration between men and women (p = 0,052) were revealed. There was not observed the dependence of the PCC content in the saliva on the age of the examined persons (R = 0.208). Conclusions. The decrease in the oral fluid PCC concentration can be induced by the decrease in the bacterial load due to preliminary sanation of the oral cavity and dilution of the saliva as a result of activation of exudation and salivation processes in periodontium tissue inflammation.