Abstract
AIM: This study aimed to evaluate the density parameters of the superficial and deep plexuses of the retina, choriocapillary layer, and avascular zone in eyes with amblyopia of various origins and paired fellow eyes.
MATERIAL AND METHODS: The study included 40 patients aged 616 (mean, 8.723.04) years. All patients were divided into 2 groups: group 1 included amblyopic, dysbinocular, and anisometropic eyes (n=48), and group 2 (control group) included paired fellow eyes without amblyopia (n=32). The density of the superficial and deep vascular plexuses of the retina, choriocapillary layer, and avascular zone parameters (area, perimeter, and circumference) were evaluated using spectral optical coherence tomography (RS-3000 Advance 2, Nidek, Japan). Correlation analysis was performed using Pearsons linear correlation coefficient (r).
RESULTS: No significant differences were found in the density of the superficial and deep retinal vessels, choriocapillary layer, and avascular zone parameters of the retina in eyes amblyopia of various origins compared with paired fellow eyes (p 0.05). No correlation was found between retinal perfusion data and functional and anatomical parameters of amblyopic eyes.
CONCLUSION: No relationship was noted between the vascular parameters of the posterior pole of the eye and the maximally corrected visual acuity, which confirms the absence of changes in retinal perfusion in amblyopia and excludes its role in the pathogenesis.
Subject
Materials Chemistry,Economics and Econometrics,Media Technology,Forestry
Reference22 articles.
1. Gerali PS, Flom MC, Raab EL. Report of the Children’s Vision Screening Task Force. Schaumburg, IL: National Society to Prevent Blindness; 1990.
2. Gilbert C, Foster A. Childhood blindness in the context of VISION 2020 — the right to sight. Bull World Health Organ. 2001;79(3):227–232.
3. Global prevalence and causes of visual impairment and blindness in children: A systematic review and meta-analysis
4. Global prevalence of amblyopia and disease burden projections through 2040: a systematic review and meta-analysis
5. Avetisov ES. Disbinokulyarnaya ambliopiya i ee lechenie. Moscow: Meditsina; 1968. (In Russ).