Abstract
The adhesion of the Tahokomb hemostatic plate of Takeda (Japan) to the solid cerebral membrane prostheses from materials of various origins was experimentally investigated to determine which of them the implants under study best provide tachocomb fixation and contribute to the prevention of postoperative liquorrhea and infectious complications resulting from leaks in the subdural space. It was found that the greatest adhesion of tachocomb was revealed to xenogenic prostheses having collagen in their composition, which characterizes them as optimal prostheses for plasticizing defects of the solid cerebral membrane from the point of view of sealing the subdural space. Intermediate values were observed in the study of prostheses of combined origin, and the lowest adhesion of tachocomb was observed with respect to synthetic prostheses. Of some interest are new composite substitutes for the hard brain (NeoDura, Medprin), created as a mix of synthetic and organic materials. The surface texture of these solid cerebral membrane analogues approaches collagen implants in characteristics, and is similar to the structure of the native solid cerebral membrane. Based on the data obtained, we can talk about the priority use of solid braincase prostheses based on animal collagen - not only due to the high adhesion parameters of tachocomb to them, but also due to other qualities: resorbability, facilitating the deposition of recipient fibroblast materials on the surface.
Reference19 articles.
1. Comparative analysis of dural reconstruction methods in open brain surgery for prevention of postoperative cerebrospinal fluid leakage
2. Comment on Arachnoid and Dura Mater Lesions
3. Odar J, Sepehrnia A, Schachtle R. Methods for repairing and regenerating human dura mater. Unaited States Patent US US8834864B2.b. 2014 Sep. 16.
4. A technique of TachoComb application in dura mater reconstruction in surgery for posterior cranial fossa tumors
5. Mustafayev BS, Mustafayeva AS. Posttraumatic liquorrhea: diagnosis and surgical treatment. Neyrokhirurgiya i nevrologiya Kazakhstana. 2017; (3):37–40. (In Russ.)