Non-alcoholic fatty liver disease and pregnancy

Abstract

The issues of epidemiology, risk factors, and pathogenetic mechanisms of non-alcoholic fatty liver disease during pregnancy are considered in the review. The impact of liver steatosis and obesity on the course and outcome of pregnancy, the perinatal state of the mother and fetus are described. Fluctuations in the hormonal spectrum, an increase in body weight, which can affect the development and progression of liver steatosis, occur during pregnancy. Women of reproductive age with metabolic syndrome, obesity require a thorough examination and, if it is necessary, optimization of metabolic health before planning pregnancy. Pregnant women with liver pathology need dynamic control and prevention of disease progression and associated obstetric complications.