Experimental studies of effectiveness of a new mineral complex for regeneration of epithelial tissues and skin

Abstract

Objective. To study the regenerative activity of a mineral complex containing ions of cerium, manganese, zinc and silver in model experiments of the planar skin wounds and acute bronchitis in laboratory animals for the development of new techniques of surgical and pulmonological diseases treatment. Materials and methods. An experimental study of the regenerative activity of a mineral complex containing ions of cerium, manganese, zinc and silver was carried out on models of the planar skin wounds and acute bronchitis in rats. Results. The results of histological examination of tissues showed the advantage of the mineral complex over the control groups of animals. The anti-inflammatory and regenerative activity of the mineral complex was established in a model of acute bronchitis and regenerative activity in a model of a planar skin wound. Conclusions. The effectiveness of the mineral complex depended on the concentration of cerium ions and was manifested at a dose of 0.003 μg/kg of animal weight.