Abstract
A clinical case of highly aggressive multiple sclerosis in a patient with a family history of demyelinating disease is presented. The effectiveness of early pathogenetic therapy by blocking the adhesion molecules of lymphocytes is demonstrated.
Reference11 articles.
1. Rasseyannyj skleroz u vzroslyh i detej: Proekt klinicheskih rekomendacij. 2020, available at: https://mapcms.ru/upload/iblock/a0f/a0f94b14685f83883eb1b7e90bd8cd95.pdf (in Russian).
2. Kasatkin D.S., Spirin N.N. Rasseyannyj skleroz v fokuse. Prikladnoe rukovodstvo. Moscow: Prakticheskaya medicina 2020 (in Russian).
3. Díaz C., Zarco L.A., Rivera D.M. Highly active multiple sclerosis: An update. Mult Scler Relat Disord. 2019 May; 30: 215–224. DOI: 10.1016/ j.msard.2019.01.039. Epub 2019. PMID: 30822617.
4. Aggressive multiple sclerosis (2): Treatment
5. Iacobaeus E., Arrambide G., Amato M.P., Derfuss T., Vukusic S., Hemmer B., Tintore M., Brundin L. 2018 ECTRIMS Focused Workshop Group. Aggressive multiple sclerosis (1): Towards a definition of the phenotype. Mult Scler. 2020; 26 (9): 1352458520925369. DOI: 10.1177/ 1352458520925369. Epub ahead of print. PMID: 32530385; PMCID: PMC7412876.