The comparative estimation cerebroprotective activity decoctions of plants genus Caragana Lam.

Abstract

The ability of herbal decoctions from 17 Caragana species to prevent retrograde amnesia of the conditioned reflex of passive avoidance after maximal electroshock (MESh) was investigated. Decoctions from 8 species were effective as antiamnestic remedies. The restoration of motor components of oriental reflex losing after MESh was accelerated by 15 from 17 species according to different indices. Decoctions from C. lacta, C. arborescens were not effective in this test. Decoctions from C. grandiflora, C. pumila, C. jubata, C. microphylla, C. stenophylla, C. altaica, C. pygmaea, C. frutex, C. spinosa, C. buriatica demonstrated higher cerebroprotective activity taking into account sum of test.