Abstract
BACKGROUND: One of the effective and pathogenetically substantiated methods of therapeutic action on cicatricial changes in the skin are laser technologies in combination with collagenases. However, as previous studies have shown, the presence of metabolic syndrome in patients significantly reduces the clinical efficacy of the combined use of laser therapy and phonophoresis of Fermencol. The most reasonable solution in this situation can be scientific research and experience in the practical use of drinking mineral waters, which have a high corrective efficiency in relation to metabolic processes, the course of which is significantly impaired in type II diabetes mellitus and metabolic syndrome.
AIMS: Assessment of clinical indicators of cicatricial changes in the skin of patients with metabolic syndrome in the combined application of the method of phonophoresis Fermenkol, fractional photothermolysis and drinking mineral waters.
MATERIAL AND METHODS: The study included 60 patients (49 men and 11 women) with cicatricial changes in the skin aged 19 to 50 years, with a confirmed diagnosis of metabolic syndrome. All patients by the method of simple fixed randomization were divided into two groups: the control group (30 people) and the main group (30 people). Both groups received treatment, which included a course of phonophoresis of 0.01% Fermencol gel in combination with the technique of fractional laser therapy. Patients of the main group, in contrast to the control group, in addition to the specified physiotherapeutic treatment received bottled sodium bicarbonate-chloride water Essentuki No. 17 (mineralization 11.8 g/l) at room temperature, 200250 ml three times a day for 1520 minutes before meals for 3 weeks.
RESULTS: The addition of physiotherapeutic combined anti-scar therapy with a course of drinking mineral water Essentuki No. 17 in patients with cicatricial changes in the skin in combination with metabolic syndrome was accompanied by a significantly more pronounced clinical effect, assessed by the Vancouver scale and the Dermatological Index of Quality of Life.
CONCLUSION: Additional course use of drinking mineral water Essentuki No. 17 is accompanied by a more pronounced dynamics of clinical manifestations of cicatricial deformities of the skin and an indicator of the quality of life of patients, due to the sanogenetic mechanisms of the drinking balneofactor.
Reference24 articles.
1. Anfilova MR. The effectiveness of intralesional injections of corticosteroids in the treatment of keloid scars. Dermatovenereology. Cosmetology. 2017;3(1):109–119. (In Russ).
2. Ilyin MV. Combined application of ultraphonophoresis of proteolytic collagenases and fractional photothermolysis in the correction of cicatricial changes in the skin [dissertation abstract]. Moscow; 2014. 24 p. (In Russ).
3. Functional improvement and thickening of quadriceps muscle and femoral intercondylar cartilage after a single intra-articular injection of a new bionic cross-linked hyaluronic acid Flexotron Cross in the treatment of knee joint osteoarthritis
4. Serebrennikova SN, Guzovskaya EV, Seminsky IZ. Nanomolecular mechanisms of metabolic syndrome formation. Transbaikal Medical Bulletin. 2019;(2):169–187. (In Russ).
5. Chursinova YV. Postoperative skin scars: the role of markers of inflammation and hypoxia (clinical and experimental study) [dissertation abstract]. Moscow; 2020. 22 p. (In Russ).
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