Clinical aspects of the applicability of biomarkers of acute kidney injury in ischemia-reperfusion in operative urology-Reference-Cited by-同舟云学术

Clinical aspects of the applicability of biomarkers of acute kidney injury in ischemia-reperfusion in operative urology

Published:2024-08-08 Issue:2 Volume:14 Page:209-216
ISSN:2687-1416
Container-title:Urology reports (St. - Petersburg)
language:
Short-container-title:Urology reports (St. - Petersburg)

Author:

Popov Sergey V.¹²³^ORCID,Guseinov Ruslan G.¹²⁴^ORCID,Sivak Konstantin V.¹⁵^ORCID,Perepelitsa Vitaliy V.¹²^ORCID,Bunenkov Nikolai S.¹⁶⁷^ORCID,Lelyavina Tatiana A.¹⁶^ORCID

Affiliation:

1. Clinical Hospital of St. Luke

2. Saint Petersburg Medical and Social Institute

3. Kirov Military Medical Academy

4. Saint Petersburg State University

5. Smorodintsev Research Institute of Influenza

6. Almazov National Medical Research Centre

7. Academician I.P. Pavlov First Saint Petersburg State Medical University

Abstract

The development of acute kidney injury during surgical renal-preserving interventions characterizes the nature of the clinical course and prognosis for the development of chronic kidney disease. The use of standard indicators of disease progression (serum creatinine and urea nitrogen) in clinical practice can lead to unfavorable outcomes of acute kidney injury due to their low sensitivity and high specificity against the background of damage to more than 50% of the renal parenchyma). Other biomarkers of acute kidney injury (cystatin C, IL-18, KIM-1, NGAL, L-FABP, NAG and others) are superior to creatinine in sensitivity and specificity, but require additional research to identify the most optimal ones for clinical practice.

Publisher

ECO-Vector LLC

Link

https://journals.eco-vector.com/uroved/article/viewFile/569117/pdf

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