Physiological status of reproductive age girls under conditions of technogenic impact in the Kola North-Reference-Cited by-同舟云学术

Physiological status of reproductive age girls under conditions of technogenic impact in the Kola North

Published:2023-02-02 Issue:12 Volume:29 Page:889-900
ISSN:2949-1444
Container-title:Ekologiya cheloveka (Human Ecology)
language:
Short-container-title:Ekologiya cheloveka (Human Ecology)

Author:

Belisheva Natalia K.^ORCID,Martynova Alla A.^ORCID,Korovkina Anna V.^ORCID

Abstract

BACKGROUND: An investigation to determine the reproductive health disorders commonly found in adolescent females residing in the North peninsula of Kola, Russia. Insubstantial studies on the physiological status of the reproductive aged females living in a territory that has become highly polluted due to the dust particles of apatite-nepheline ore, determines the relevance of this study and involves the identification of indicators of premorbid state. AIM: To examine the physiological status of reproductive aged females living under chronic stress condition caused by exposure to both anthropogenic as well as Arctic environment with an objective to reveal possible pre-nosological deviations as indicators of premorbid state. MATERIAL AND METHODS: We conducted an observational, longitudinal analytic "3 waves panel study (2019, 2020, 2021) involving 54 female students 1620 years old from medical college in the city of Apatity, Russia. Physiological status was assessed in accordance with the content of hypothalamic-pituitary-adrenocortical system hormones, metabolites of lipid peroxidation, antioxidant protection, vitamin D, lipids, and carbohydrates using percentile distribution of indicator values. Significance of the differences was determined by comparative analysis of two dependent variables using the Wilcoxon criterion. RESULTS: Deviations from the optimal values of physiological state indicators were revealed in more than 25% of the females, which manifested themselves in increased secretion of adrenocorticotropic hormone, cortisol, thyrotropic hormone, and depleting secretion of somatotropic hormone, thyroxine with reduced content of antioxidant protection enzymes. In 95% of females, hypovitaminosis of vitamin D was detected whereas 50% of females were found with diminished values of low-density lipoproteins. CONCLUSION: Pre-nosological deviations of the physiological status in the conditions of technogenic pollution testify to the oppression of the bodys protective systems and are predictors of morbidity and are subject to individual correction.

Publisher

ECO-Vector LLC

Subject

General Medicine,Public Health, Environmental and Occupational Health,Ecology,Health (social science)

Link

https://hum-ecol.ru/1728-0869/article/viewFile/109941/pdf_2

Reference30 articles.

1. Sokolovskaya TA. Gender aspects of reproductive health of children in the Russian Federation. Preventive and Clinical Medicine. 2014;(2):19–25. (In Russ).

2. Grigoryev YuA, Soboleva SV. Reproductive health as qualitative population characteristics. Acta Biomedica Scientifica (East Siberian Biomedical Journal). 2013;(3-2):157–161. (In Russ).

3. Kolesnikova LI, Grebenkina LA, Darenskaya MA, Vlasov BY. Oxidative stress as nonspecific pathogenetic link of reproductive disorders (systematic review). The Bulletin of Siberian Branch of Russian Academy of Medical Sciences. 2012;32(1):58–66. (In Russ).

4. Deryagin GB, Sidorov PI, Soloviev AG. Puberty features of European and Ural-Mongol women In the North of Russia. Seksologiya i seksopatologiya. 2005;(4):37–41. (In Russ).

5. Belisheva NK. Contribution of high latitude heliogeophysical agents in the morbidity of the population of the Euro-Arctic region. Journal of Ural Medical Academic Science. 2014;(2):5–11. (In Russ).