C. difficile toxins A and B from the clinician's viewpoint

Abstract

To date, C. difficile is considered as an etiological factor in pseudomembranous colitis and antibiotic-associated diarrhea as well as the main cause of nosocomial diarrhea spread mainly in economically developed countries. The complexity of laboratory and experimental studies of infection is what the microbe cannot be genetically manipulated. At the same time, the most of hospital and municipal laboratories have no the possibility to carry out research on detection C. difficile toxins, that limits the resource of real estimation of the spread of the disease in the Russian Federation.