POTENTIAL ROLE OF INTRAVITAL ARTERIAL EMBOLOGENIC THROMBI ON CARDIO-VASCULAR CATASTROPHIC EVENTS ACCORDING TO POSTMORTEM INVESTIGATIONS

Abstract

Aim. The purpose of our study was to value the role of potential arterial emboli sources in death cause according to postmortem data collected in deceased from all causes in a multifield hospital.Material and methods. We performed retrospective analysis of 1324 postmortem records of died pa- tients for the past 6 years (2011-2016). We registered patients’ age and sex, thrombus site, definite intravital clinical and anamnestic data, individual features of tanathogenesis.Results. Intravital thrombus formation was found in 64 of died patients (4,8%), mean age 73,9±2,7 years, women 51,5%. In 41 patients (1 group) there were firm wall thrombi in aorta, in 23 patients thrombi were found in heart cameras (2 group), mostly in left atrial appendage (LAA). Generalized atherosclerosis presented more often in 1 group - 95,5% vs 39,1 in 2 group (p<0,005). The most com- mon cause of death in both groups was acute myocardial infarction. In 1 group infarction was often in combination with acute blood supply disturbances in various arterial regions. For deceased of 2 group thromboembolic fatal events were more typical.Conclusion. It was found that the most dangerous thrombi regarding thromboembolic events were intracardiac ones, mainly in LAA. Aortic wall thrombi have become the marker of generalized athero- sclerosis. The last ones predetermined high probability of ischemic complications in multivessel areas.