Humus acids are promising compounds for the creation of new antimicrobial drugs

Author:

Benderskii Nikita S.ORCID,Popov Zahar S.ORCID,Popova Darya A.ORCID,Movchan Elena L.ORCID,Anuchina Elizabeth A.ORCID,Shiryaeva Valeria S.ORCID,Kozlovtseva Julia V.ORCID,Noskova Maria A.ORCID,Uzdenova Diana S.ORCID,Gantsgorn Elena V.ORCID,Kudelina Oksana M.ORCID

Abstract

Infectious diseases are still the leading causes of morbidity and mortality worldwide, which prompts the need to prioritize research and development of new antimicrobial drugs with high pharmacological activity and favorable safety profile. One of the key directions in this field is the study of the potential of natural compounds, such as humus acids. Recent studies have shown that humus acids can exhibit multidirectional activity against various microorganisms and demonstrate synergistic pharmacological interaction with other drugs. This review aimed to present a generalized and systematic analysis of currently available information on the known pharmacological effects and possible mechanisms of the antibacterial, antiviral, and antifungal activities of humus acids.

Publisher

ECO-Vector LLC

Subject

General Medicine

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