Current understanding of complex regional pain syndrome

Abstract

Complex regional pain syndrome (CRPS) is a multifactorial pathology characterized by chronic pain, autonomic disorders, and motor dysfunction. This review discusses the mechanisms of CRPS development, as well as methods of its diagnosis, treatment, and prevention. In addition to drug treatment and physical therapy, issues of interventional methods for the treatment of CRPS are also covered. Along with sympathetic blocks and various ablation techniques under ultrasound and fluoroscopic guidance, a new waveform for spinal cord stimulation and new stimulation targets such as dorsal root ganglia have been proposed.