Adenomyosis and fertility: a modern view of the problem. A literature review

Author:

Bezhenar Vitaly F.ORCID,Linde Viktor A.ORCID,Arakelyan Byuzand V.ORCID,Kalugina Alla S.ORCID,Vasilyev Yuri V.ORCID,Sobakina Darya A.ORCID,Sadykhova Elmina E.ORCID,Tarasenkova Viktoria A.ORCID

Abstract

This literature review is based on resources from the following databases: CyberLeninka, PubMed, MedArt, and the Central Scientific Medical Library (I.M. Sechenov First Moscow State Medical University, Moscow, Russia). Adenomyosis is a common non-infectious uterine pathology associated with the risk of infertility and obstetric problems. The local inflammation that develops in adenomyosis reduces the probability of blastocyst implantation and creates an unfavorable environment for the development of the embryo. Adenomyosis reduces the effectiveness of assisted reproductive technology. During the pregnancy in adenomyosis, the risk of incomplete and prolonged pregnancy increases at almost all stages. Besides, the risk of massive hemorrhage increases during pregnancy, childbirth and the early postpartum period. The presented review helps to assess the pathogenetic mechanisms underlying the negative effect of adenomyosis on womens fertility based on data obtained over the past ten years.

Publisher

ECO-Vector LLC

Subject

Obstetrics and Gynecology

Reference64 articles.

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3. Jendometrioz. Klinicheskie rekomendacii. Moscow, 2020. [cited 5 Dec 2021]. Available from: https://www.dzhmao.ru/spez/klin_recom/akushGinekol/2020/KR_259_endometrioz.pdf

4. Abaykhanova LM. Uterine adenomyosis − symptoms and treatment. In: Science. Education. Innovations: Collection of scientific papers based on the materials of the XII International Scientific and Practical Conference. Anapa; 2019:51−54. [cited 6 Dec 2021]. Available from: https://innova-science.ru/wp-content/uploads/2019/11/sbornik-nauchnyh-trudov-12.11.2019-noi-12.pdf

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