Biochemical parameters of amniotic fluid in fetal distress during delivery

Abstract

Aim. Amniotic fluid is the unique biological medium that reflects the activity of the fetoplacental complex. The aim of our study was to examine a wide range of biochemical parameters of amniotic fluid to detect factors for fetal distress during labor.Materials and methods. The article presents the data of anterior and posterior amniotic fluid biochemical examination of women with full-term pregnancy. The main group consisted of patients who have experienced fetal distress during labor according to the CTG parameters and acid base balance parameters of cord blood during labor. The control group consisted of mothers without fetal distress.Results. We found that in fetal distress during labor the anterior amniotic fluid have lower levels of total protein, triglycerides, gamma-glutamyl transferase, alpha-amylase, iron. Creatinine was higher in the posterior amniotic fluid. Conclusion. Biochemical examination of amniotic fluid may provide additional valuable information of fetal and fetoplacental complex condition.