Videoendolaringeal'naya khirurgiya i fotodinamicheskaya terapiya s ispol'zovaniem gibkoy endoskopicheskoy tekhniki pri predrake i rannem rake gortani

Author:

Sokolov V V,Telegina L V,Gladyshev A A,Reshetov I V,Ol'shanskiy V O,Golubtsov A K

Abstract

The authors have developed and used a number of endolaryngeal surgical procedures for the treatment of patients with laryngeal precancer and cancer (LC), by using flexible video-assisted endoscopic technology, Nd:YAG laser thermoablation, argon plasma coagulation, electric resection, and photodynamic therapy. In 1987 to 2008, endolaryngeal surgery was performed in 129 patients, including 23 with dyskeratosis with laryngeal dysplasia, 36 with virus-associated recurrent laryngeal papillomatosis, 37 with early cancer of the midlarynx (Tis - T1N0M0), 17 with residual tumor, and 16 with local recurrent cancer of the midlarynx (T1-2N0M0) after teleradiotherapy. The therapy resulted in complete regression (CR) of dyskeratosis and first-to-third degree dysplasia in 22 (95%) of the 23 patients. CR was achieved in 27 (75%) of the 36 patients in the recurrent laryngeal papillomatosis group. Persistent remission and human papillomavirus eradication were brought about in 70% of cases. CR was obtained in 34 (92%) of the 37 patients in the primary LC group. Recurrent LC was found in 3 (9%) of the 34 patients. Complete recovery of vocal cord function recovery was noted in all cases. CR could be achieved in 27 (82%) in the residual and recurrent laryngeal tumor groups (n = 33). Recurrent LC was detected in 3 patients 1-5 years after treatment completion.

Publisher

ECO-Vector LLC

Subject

General Medicine

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