Varicocele and its effect on fertility

Author:

Zamyatnin Sergey A.,Gonchar Irina S.,Schmidt Andrey A.

Abstract

Varicocele is recognized as one of the most common urological diseases, but its true prevalence is a matter of debate. In the present study, during a screening examination of 442 young men (mean age 21.6 years), grade I varicocele was detected in 7.2%, grade II in 42.1%, and grade III in 15.2% of men, varicocele was absent only in 35.5% of men. In 41% of cases, varicocele was diagnosed in isolation on the left side, in 36.5% of cases, bilateral varicocele was detected, and in 22.5%, varicose veins of the spermatic cord were detected on the right. Pathozoospermia was found in 47.3% of patients with grade II varicocele and 61.2% with grade III varicocele. The data obtained in the course of the study showed a significant effect of varicocele and its duration on sperm quality, in particular, on sperm morphology.

Publisher

ECO-Vector LLC

Reference19 articles.

1. Major protein alterations in spermatozoa from infertile men with unilateral varicocele

2. Proteomic analysis of seminal plasma from bilateral varicocele patients indicates an oxidative state and increased inflammatory response

3. Alyaev YuG, Glybochko PV, Pushkar’ DYu. Urologiya. Rossiiskie klinicheskie rekomendatsii. Moscow: GEOTAR-Media. 2016. 496 p. (In Russ.)

4. Madykin YY, Zolotuhin OV. Varicocele and fertility disorders. Journal of New Medical Technologies. 2013;(2):269–270. (In Russ.)

5. Shmidt АА, Zamyatnin SA, Gonchar IS, Korovin AE. Risk factors of the development of male infertiality. Clinical Pathophysiology. 2019;(4):41–45. (In Russ.)

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