Integral role of metabolic profiling in patients with prostate cancer

Author:

Pavlov Valentin N.1ORCID,Urmantsev Marat F.1ORCID,Bakeev Marat R.1ORCID

Affiliation:

1. Bashkir State Medical University

Abstract

Prostate cancer is the most diagnosed malignant neoplasm among males worldwide. Over the past few years, there has been a need to find alternative methods for early diagnosis of prostate cancer. There is evidence that metabolic dysfunction is a characteristic feature of the carcinogenesis of prostate cancer, with various metabolites acting as biomarkers of tumor growth. Metabolomics is a young science that arose at the junction of molecular biology, biochemistry and genetics. The complete set of substrates and metabolic products is a metabolic profile, or metabolome. The metabolome of prostate cancer is formed by substances formed as a result of metabolic changes in response to the occurrence of a malignant process in the prostate. Unique data on metabolic changes have already been obtained, allowing us to rethink the carcinogenesis of prostate cancer. The study of the metabolome opens up new opportunities for early diagnosis, prognosis and treatment of prostate cancer.

Publisher

ECO-Vector LLC

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