Affiliation:
1. Pirogov Russian National Research Medical University
2. Academician I.P. Pavlov First St. Petersburg State Medical University
Abstract
The review article shows the main stages of studying botulinum toxin and its use in medicine. The possibilities of using botulinum toxin for the treatment of urological patients are similarly described. Furthermore, the most significant studies on the use of botulinum toxin in patients with neurogenic detrusor c, idiopathic overactive bladder, detrusor sphincter dyssynergia, chronic pelvic pain, benign prostatic hyperplasia, erectile dysfunction, and premature ejaculation are presented.
Reference65 articles.
1. Grüsser OJ. The first systematic descriptions and animal experiment studies of botulism. On the 200th birthday of Justinus Kerner 18 September 1986. Sudhoffs Arch. 1986;70(2):167–287. (In German)
2. Kerner J. Vergiftung durch verdorbene Würste. Tübinger Blätter für Naturwissenschaften und Arzneykunde. 1817;3:1–25. (In German)
3. Historical aspects of botulinum toxin: Justinus Kerner (1786-1862) and the "sausage poison"
4. On the Discovery of Clostridium botulinum
5. Ueber einen neuen anaëroben Bacillus und seine Beziehungen zum Botulismus