Acquired overt cytomegalovirus infection in immunocompetent adult patients

Abstract

There has been analyzed the clinical course of the disease in 94 hospitalized patients with acute acquired overt cytomegalovirus infection, confirmed by serological tests and polymerase chain reaction. Males of young age were shown to suffer more often. In the clinical picture symptoms of intoxication (fever, weakness), hepatomegaly with increased activity of liver enzymes, splenomegaly, the involvement of the airways and lymph nodes available for palpation prevail. The clinical feature of the overt form of cytomegalovirus infection is a frequent combination with infection caused by the Epstein-Barr virus. The comprehensive treatment with introduction of antiviral drugs leads to normalization of temperature, removal of organ lesions and improvement of the patients .