Cyclodestructive interventions in refractory glaucoma treatment: history, reality, perspectives

Abstract

This article presents a historical evolution review of cyclodestructive methods in glaucoma treatment. It also provides the analysis of mechanism of action for each technology, their advantages and disadvantages. Results of clinical studies and most frequent complications of cyclodestructive procedures are also presented. The main attention is paid to the new MicroPulse laser technology, which is used for the treatment of primary open-angle glaucoma at various stages in patients with high visual acuity, as well as refractory forms of glaucoma. Data of clinical and experimental morphological studies of various modifications of transscleral cyclophotocoagulation technology are specified. Theories, research hypothesis upon the mechanism of MicroPulse laser action. In most researchers opinion, despite the relatively short observation period (from 6 months to 5 years), MicroPulse technology is recognized as effective and advanced.