Affiliation:
1. I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
2. I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
3. I.M. Sechenov First Moscow State Medical University (Sechenov University)
Abstract
Atopic dermatitis is an autoinflammatory, genetically determined, itchy disease characterized by a long, relapsing course and a sharp decrease in the patient’s quality of life. Atopic dermatitis (AD) is caused by a complex interaction of immune dysregulation, epidermal gene mutations, and multi-environmental factors that affect the skin, causing intense itchy rashes. The disease often occurs among young children and subsequently has age-related clinical features. Currently, the treatment of atopic dermatitis has a wide range of options, including drugs from the group of small molecules recently registered in the Russian Federation. The first clinical experience with the use of abrocitinib in adult patients with atopic dermatitis is presented.