Treatment of spermatologic disorders and oxidative stress after reproductively significant diseases caused by sexually transmitted infection

Abstract

This study evaluated the efficacy and safety of two organic dietary supplements, AndroDoz and Testogenon, in the treatment of 58 men with spermatologic disorders and oxidative stress after experiencing reproductively significant diseases caused by sexually transmitted infection. Over a 12 week period, 38 patients (test group) received both AndroDoz and Testogenon as a combination therapy, whereas 20 patients (control group) received AndroDoz alone. The combination therapy with both AndroDoz and Testogenon showed a statistically significant increase in treatment effectiveness. A positive clinical effect was noted in 92.2% of patients in the test group who received combination therapy. This was reflected as an increased concentration and mobility level of spermatozoa, similar to values observed in men with normozoospermia. Moreover, these men exhibited a two-fold reduction in the risk of fertility disorders due to DNA fragmentation in spermatozoa; their testosterone also increased to normal levels. Additionally, patients in the test group showed improvement in the quality of erection and increased blood flow in the prostate gland and testicles. Men in the control group, who received monotherapy with AndroDoz, did not show improvement similar to that of men in the test group; normozoospermia was established in 70% of men in the control group. These results confirm that AndroDoz and Testogenon are more effective when used concomitantly. These supplements showed no side effects and could be used in complex treatment of spermatologic disorders and oxidative stress in men who experienced reproductively significant diseases caused by sexually transmitted infection. (For citation: Kalinina SN, Korenkov DG, Fesenko VN. Treatment of spermatologic disorders and oxidative stress after reproductively significant diseases caused by sexually transmitted infection. Urologicheskie vedomosti. 2018;8(4):5-15. doi: 10.17816/uroved845-15).