Nutritive status changes, studied in hiv-positive patients with pneumonias, caused by Streptococcus pneumoniae

Abstract

Aim. To study the changes in nutritive status of HIV-positive patients, hospitalized with community-acquired pneumonias, caused by Streptococcus pneumoniae. Materials and methods. During 2014–2017, clinicolaboratory examination of 676 HIV-positive patients was carried out on the basis of Perm Regional Clinical Infectious Hospital. There were formed the groups of “observation”, including patients with pneumonias, caused by Streptococcus pneumoniae with lethal outcomes, and groups of “comparison”, including patients, discharged from hospital in satisfactory status. Results. Negative dynamics of nutritive status, caused by progression of the main disease and addition of bacterial agent was revealed. The moderately severe and severe changes were registered in patients with lethal outcomes already at the moment of hospitalization. Conclusions. Direct correlation between the protein-energy insufficiency and the number of life-threatening complications was determined.