The effect of excess body weight and obesity on the effectiveness of assisted reproductive technologies programs

Abstract

The purpose of the study. To determine the main indicators of the effectiveness of IVF programs in over-weight and obese patients. Based on the Research Institute of obstetrics, gynecology, and reproductology D.O. Ott, we conducted an analysis involving women aged 18–39 years who were treated in the IVF program in the department of assistive technologies in infertility treatment. The study included 97 patients who met the selection criteria. The patients were categorized into three groups: group I, 33 obese women (body mass index (BMI) ≥ 30.8 kg/m2); group II, 34 overweight women (BMI = 25 to 29.9 kg/m2); and the control group, 30 normal weight patients (BMI = 18 to 24.9 kg/m2). As a result, the efficiency of ART programs decreased significantly in women of group I, owing to the weaker response of the ovaries to the stimulation of superovulation, which causes an increased gonadotropin demand to stimulate  ovulation.