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Efficacy and Safety of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia

  • Published:2017 Issue:4 Volume:24 Page:402-411
  • ISSN:1340-3478
  • Container-title:Journal of Atherosclerosis and Thrombosis
  • language:en
  • Short-container-title:JAT

Author:

Harada-Shiba Mariko1,Ikewaki Katsunori2,Nohara Atsushi3,Otsubo Yoshihiko4,Yanagi Koji5,Yoshida Masayuki6,Chang Qing7,Foulds Pamela7

Affiliation:

1. National Cerebral and Cardiovascular Research Center

2. National Defense Medical College

3. Kanazawa University Graduate School of Medical Sciences

4. Shin-Koga Clinic, Medical Group Tenjin-kai

5. Kenporen Osaka Central Hospital

6. Tokyo Medical and Dental University

7. Aegerion Pharmaceuticals, Inc.

Publisher

Japan Atherosclerosis Society

Subject

Biochemistry (medical),Cardiology and Cardiovascular Medicine,Internal Medicine

Reference29 articles.

1. 1) Cuchel M, Bruckert E, Ginsberg HN, Raal FJ, Santos RD, Hegele RA, Kuivenhoven JA, Nordestgaard BG, Descamps OS, Steinhagen-Thiessen E, Tybjaerg-Hansen A, Watts GF, Averna M, Boileau C, Boren J, Catapano AL, Defesche JC, Hovingh GK, Humphries SE, Kovanen PT, Masana L, Pajukanta P, Parhofer KG, Ray KK, Stalenhoef AF, Stroes E, Taskinen MR, Wiegman A, Wiklund O, Chapman MJ: Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Eur Heart J, 2014; 35: 2146-2157

2. 2) Beigel R, Beigel Y: Homozygous familial hypercholesterolemia: long term clinical course and plasma exchange therapy for two individual patients and review of the literature. J Clin Apher, 2009; 24: 219-224

3. 3) Hobbs HH, Brown MS, Goldstein JL: Molecular genetics of the LDL receptor gene in familial hypercholesterolemia. Hum Mutat, 1992; 1: 445-466

4. 4) Kolansky DM, Cuchel M, Clark BJ, Paridon S, McCrindle BW, Wiegers SE, Araujo L, Vohra Y, Defesche JC, Wilson JM, Rader DJ: Longitudinal evaluation and assessment of cardiovascular disease in patients with homozygous familial hypercholesterolemia. Am J Cardiol, 2008; 102: 1438-1443

5. 5) Gidding SS, Ann Champagne M, de Ferranti SD, Defesche J, Ito MK, Knowles JW, McCrindle B, Raal F, Rader D, Santos RD, Lopes-Virella M, Watts GF, Wierzbicki AS, and on behalf of the American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young, Council on Cardiovascular and Stroke Nursing, Council on Functional Genomics and Translational Biology, and Council on Lifestyle and Cardiometabolic Health: The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association. Circulation, 2015; 132: 2167-2192
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