Cumulative Effects of LDL Cholesterol and CRP Levels on Recurrent Stroke and TIA

Author:

Kitagawa Kazuo1,Hosomi Naohisa2,Nagai Yoji3,Kagimura Tatsuo4,Ohtsuki Toshiho5,Maruyama Hirofumi2,Origasa Hideki6,Minematsu Kazuo7,Uchiyama Shinichiro8,Nakamura Masakazu7,Matsumoto Masayasu29,

Affiliation:

1. Department of Neurology, Tokyo Women’s Medical University

2. Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences

3. Clinical and Translational Research Center, Kobe University Hospital

4. Foundation for Biomedical Research and Innovation at Kobe, Translational Research Center for Medical Innovation

5. Stroke Center, Kindai University Hospital

6. Division of Biostatistics and Clinical Epidemiology, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences

7. National Cerebral and Cardiovascular Center

8. Clinical Research Center, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Medical Center

9. Sakai City Medical Center, Sakai City Hospital Organization

Publisher

Japan Atherosclerosis Society

Subject

Biochemistry (medical),Cardiology and Cardiovascular Medicine,Internal Medicine

Reference18 articles.

1. 1) Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH, Goldberg AC, Gordon D, Levy D, Lloyd-Jones DM, McBride P, Schwartz JS, Shero ST, Smith SC Jr, Watson K, Wilson PW, Eddleman KM, Jarrett NM, LaBresh K, Nevo L, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK, Smith SC Jr, Tomaselli GF. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation, 2014; 129 (25 Suppl 2): S1-45

2. 2) Ridker PM. From C-reactive protein to Interleukin-6 to Interleukin-1: Moving Upstream to Identify Novel Targets for Atheroprotection. Circ Res, 2016; 118: 145-156

3. 3) Albert MA, Danielson E, Rifai N, Ridker PM. Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. JAMA, 2001; 286: 64-70

4. 4) Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med, 2008; 359: 2195-2207

5. 5) Hosomi N, Nagai Y, Kohriyama T, Ohtsuki T, Aoki S, Nezu T, Maruyama H, Sunami N, Yokota C, Kitagawa K, Terayama Y, Takagi M, Ibayashi S, Nakamura M, Origasa H, Fukushima M, Mori E, Minematsu K, Uchiyama S, Shinohara Y, Yamaguchi T, Matsumoto M; J-STARS Collaborators. A Multicenter, Randomized, Open-label, Parallel-group Study. EBioMedicine, 2015; 2: 1071-1078

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