Therapeutic Angiogenesis Induced by Hepatocyte Growth Factor : Potential Gene Therapy for Ischemic diseases

Author:

Aoki Motokuni,Morishita Ryuichi,Taniyama Yoshiaki,Kaneda Yasufumi,Ogihara Toshio

Publisher

Japan Atherosclerosis Society

Subject

Biochemistry, medical,Cardiology and Cardiovascular Medicine,Internal Medicine

Reference29 articles.

1. (1) Bussolino F, Di Renzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagnone L, Coffer A, and Comoglio PM : Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol, 119 : 629-641, 1992

2. (2) Nakamura Y, Morishita R, Nakamura S, Aoki M, Moriguchi A, Matsumoto K, Nakamura T, Higaki J, and ogihara T : A vascular modulator, hepatocyte growth factor, is associated with systolic pressure. Hypertension, 28 : 409-413, 1996

3. (3) Hayashi S, Morishita R, Higaki J, Aoki M, Moriguchi A, Kida I, Sawa Y, Matsumoto K, Nakamura T, Kaneda Y, and Ogihara T : Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells. Biochem Biophys Res Commun, 220 : 539-545, 1996

4. (4) Nakamura Y, Morishita R, Higaki J, Kida I, Aoki M, Moriguchi A, Yamada K, Hayashi S, Yo Y, Nakano H, Matsumoto K, Nakamura T, and Ogihara T : Hepatocyte growth factor is a novel member of the endotheliumspecific growth factors : additive stimulatory effect of hepatocyte growth factor with basic fibroblast growth factor but not with vascular endothelial growth factor. J Hypertens, 14 : 1067-1072, 1996

5. (5) Hayashi S, Morishita R, Nakamura S, Yamamoto K, Moriguchi A, Nagano T, Taiji M, Noguchi H, Matsumoto K, Nakamura T, Higaki J, and Ogihara T : Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease : downregulation of HGF in response to hypoxia in vascular cells. Circulation, 100 (suppl II) : 11-301-11-308, 1999

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