Gradual dose Titration of Lomitapide may Prevent Therapeutic Delays in Patients with Homozygous Familial Hypercholesterolemia
Author:
Affiliation:
1. Cardiovascular Center, Osaka Medical and Pharmaceutical University
2. Division of Endocrinology and Metabolism, National Cerebral and Cardiovascular Center
3. Department of Metabolism and Endocrinology, Eastern Chiba Medical Center
Publisher
Japan Atherosclerosis Society
Subject
Biochemistry (medical),Cardiology and Cardiovascular Medicine,Internal Medicine
Link
https://www.jstage.jst.go.jp/article/jat/30/2/30_LE003/_pdf
Reference9 articles.
1. 1) Defesche JC, Gidding SS, Harada-Shiba M, Hegele RA, Santos RD and Wierzbicki AS. Familial hypercholesterolaemia. Nat Rev Dis Primer, 2017; 3: 17093
2. 2) Nohara A, Tada H, Ogura M, Okazaki S, Ono K, Shimano H, Daida H, Dobashi K, Hayashi T, Hori M, Matsuki K, Minamino T, Yokoyama S and Harada-Shiba M. Homozygous Familial Hypercholesterolemia. J Atheroscler Thromb, 2021; 28: 665-678
3. 3) Nordestgaard BG, Chapman MJ, Humphries SE, Ginsberg HN, Masana L, Descamps OS, Wiklund O, Hegele RA, Raal FJ, Defesche JC, Wiegman A, Santos RD, Watts GF, Parhofer KG, Hovingh GK, Kovanen PT, Boileau C, Averna M, Boren J, Bruckert E, Catapano AL, Kuivenhoven JA, Pajukanta P, Ray K, Stalenhoef AF, Stroes E, Taskinen MR, Tybjaerg-Hansen A and European Atherosclerosis Society Consensus P. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J, 2013; 34: 3478-90a
4. 4) Harada-Shiba M, Arai H, Ishigaki Y, Ishibashi S, Okamura T, Ogura M, Dobashi K, Nohara A, Bujo H, Miyauchi K, Yamashita S, Yokote K and Working Group by Japan Atherosclerosis Society for Making Guidance of Familial H. Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017. J Atheroscler Thromb, 2018; 25: 751-770
5. 5) Makino H, Koezuka R, Tamanaha T, Ogura M, Matsuki K, Hosoda K and Harada-Shiba M. Familial Hypercholesterolemia and Lipoprotein Apheresis. J Atheroscler Thromb, 2019; 26: 679-687
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1. The first Japanese case with familial combined hypolipidemia without any complications caused by loss-of function variants in ANGPTL3: Case report;Heliyon;2024-04
2. Genetic Counseling and Genetic Testing for Familial Hypercholesterolemia;Genes;2024-02-26
3. Real-world safety and efficacy of lomitapide in homozygous familial hypercholesterolemia: interim report of special-use survey in Japan;Future Cardiology;2024-02
4. Clinical Characteristics of Homozygous Familial Hypercholesterolemia in Japan;JACC: Asia;2023-12
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