Serum Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is Independently Associated with Insulin Resistance, Triglycerides, Lipoprotein(a) Levels but not Low-Density Lipoprotein Cholesterol Levels in a General Population
Author:
Affiliation:
1. Department of Internal Medicine, Division of Cardio-Vascular Medicine, Kurume University School of Medicine
2. Department of Community Medicine, Kurume University School of Medicine
Publisher
Japan Atherosclerosis Society
Subject
Biochemistry, medical,Cardiology and Cardiovascular Medicine,Internal Medicine
Link
https://www.jstage.jst.go.jp/article/jat/28/4/28_56390/_pdf
Reference38 articles.
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2. 2) Baass A, Dubuc G, Tremblay M, Delvin EE, O’Loughlin J, Levy E, Davignon J, Lambert M: Plasma PCSK9 is associated with age, sex, and multiple metabolic markers in a population-based sample of children and adolescents. Clin Chem, 2009; 55: 1637-1645
3. 3) Chan DC, Pang J, McQuillan BM, Hung J, Beilby JP, Barrett PH, Watts GF: Plasma proprotein convertase subtilisin kexin type 9 as a predictor of carotid atherosclerosis in asymptomatic adults. Heart Lung Circ, 2016; 25: 520-525
4. 4) Victor RG, Haley RW, Willett DL, Peshock RM, Vaeth PC, Leonard D, Basit M, Cooper RS, Iannacchione VG, Visscher WA, Staab JM, Hobbs HH; Dallas Heart Study Investigators: The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health. Am J Cardiol, 2004; 93: 1473-1480
5. 5) Miao J, Manthena PV, Haas ME, Ling AV, Shin DJ, Graham MJ, Crooke RM, Liu J, Biddinger SB: Role of insulin in the regulation of proprotein convertase subtilisin/kexin type 9. Arterioscler Thromb Vasc Biol, 2015; 35: 1589-1596
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1. Mediation effect of metabolic factors and inflammation on the association of serum uric acid with serum proprotein convertase subtilisin/kexin type 9 levels;Journal of Clinical Lipidology;2024-05
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3. Safety and Efficacy of Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors After Acute Coronary Syndrome: A Meta-analysis of Randomized Controlled Trials;American Journal of Cardiovascular Drugs;2024-01
4. Lipoproteins, Cholesterol, and Atherosclerotic Cardiovascular Disease in East Asians and Europeans;Journal of Atherosclerosis and Thrombosis;2023-11-01
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