Prediction of Molecular Interaction between Platelet Glycoprotein Ibα and von Willebrand Factor using Molecular Dynamics Simulations
Author:
Affiliation:
1. Department of Medicine (Cardiology), Tokai University School of Medicine
2. Department of Mechanical Engineering, The University of Tokyo
Publisher
Japan Atherosclerosis Society
Subject
Biochemistry (medical),Cardiology and Cardiovascular Medicine,Internal Medicine
Link
https://www.jstage.jst.go.jp/article/jat/23/4/23_32458/_pdf
Reference57 articles.
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2. 2) Andre P, Denis CV, Ware J, Saffaripour S, Hynes RO, Ruggeri ZM and Wagner DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood. 2000; 96: 3322-3328
3. 3) McGhie AI, McNatt J, Ezov N, Cui K, Mower LK, Hagay Y, Buja LM, Garfinkel LI, Gorecki M and Willerson JT. Abolition of cyclic flow variations in stenosed, endothelium-injured coronary arteries in nonhuman primates with a peptide fragment (VCL) derived from human plasma von Willebrand factor-glycoprotein Ib binding domain. Circulation. 1994; 90: 2976-2981
4. 4) Savage B, Saldivar E and Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell. 1996; 84: 289-297
5. 5) Goto S, Ikeda Y, Saldivar E and Ruggeri ZM. Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. J Clin Invest. 1998; 101: 479-486
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