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How Can We Identify Very High-Risk Heterozygous Familial Hypercholesterolemia?

  • Published:2022-06-01 Issue:6 Volume:29 Page:795-807
  • ISSN:1340-3478
  • Container-title:Journal of Atherosclerosis and Thrombosis
  • language:en
  • Short-container-title:JAT

Author:

Kataoka Yu1,Funabashi Sayaka2,Doi Takahito3,Harada-Shiba Mariko4

Affiliation:

1. Department of Cardiovascular Medicine, National Cerebral & Cardiovascular Centre

2. Department of Cardiology, Kyorin University School of Medicine

3. Department of Clinical Biochemistry, Copenhagen University Hospital, Herlev and Gentofte

4. Department of Molecular Innovation in Lipidology, National Cerebral & Cardiovascular Centre

Publisher

Japan Atherosclerosis Society

Subject

Biochemistry (medical),Cardiology and Cardiovascular Medicine,Internal Medicine

Reference63 articles.

1. 1) Nordestgaard BG, Chapman MJ, Humphries SE, Ginsberg HN, Masana L, Descamps OS, Wiklund O, Hegele RA, Raal FJ, Defesche JC, Wiegman A, Santos RD, Watts GF, Parhofer KG, Hovingh GK, Kovanen PT, Boileau C, Averna M, Borén J, Bruckert E, Catapano AL, Kuivenhoven JA, Pajukanta P, Ray K, Stalenhoef AF, Stroes E, Taskinen MR, Tybjærg-Hansen A; European Atherosclerosis Society Consensus Panel: Familial hypercholesterolaemia is underdiagnosed and undertreated in the general popu- lation: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J, 2013; 34: 3478-3490a

2. 2) Langsted A, Kamstrup PR, Benn M, Tybjaerg- Hansen A, Nordestgaard BG: High lipoprotein(a) as a possible cause of clinical familial hyper- cholesterolaemia: a prospective cohort study. Lancet Diabetes Endocrinol, 2016; 4: 577-587

3. 3) Brown MS, Goldstein JL: A receptor-mediated pathway for cholesterol homeostasis. Science, 1986; 232: 34-47

4. 4) Hopkins PN, Toth PP, Ballantyne CM, Rader DJ: Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol, 2011; 5: S9-S17

5. 5) Gidding SS, Champagne MA, de Ferranti SD, Defesche J, Ito MK, Knowles JW, McCrindle B, Raal F, Rader D, Santos RD, Lopes-Virella M, Watts GF, Wierzbicki AS; American Heart Association Atherosclerosis, Hypertension, and Obesity in Young Committee of Council on Cardiovascular Disease in Young, Council on Cardiovascular and Stroke Nursing, Council on Functional Genomics and Translational Biology, and Council on Lifestyle and Cardiometabolic Health: The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association. Circulation, 2015; 132: 2167-2192

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