Use of dielectric nanoparticles doped with Yb3+ ions to enhance the thermal effect in a biological tissue exposed to near-IR laser radiation (in vivo experiments)

Abstract

Abstract The conditions for the appearance of broadband radiation from particles of zirconium dioxide stabilised by ytterbium oxide upon excitation by intense laser radiation with a wavelength of 980 nm are investigated. It is shown that this radiation is observed at a lower excitation power density and lower ytterbium content than in particles of orthophosphates and their hydrates. As a result of in vivo experiments, the possibility of using ytterbium-containing particles to enhance the thermal effect from exposure to laser radiation with a wavelength of 980 nm on the skin of a rat is demonstrated.