APOPTOTIC AND PROINFLAMMATORY PROCESSES ESTIMATION IN PATIENTS WITH DIABETIC NEUROPATHY

Author:

Obraztsova I.A.1,Popov S.S.2,Verevkin A.N.3,Pashkova A.A.4,Kryl'skii E.D.5,Popova T.N.5

Affiliation:

1. Department of Polyclinic Therapy, Voronezh State Medical University named after N.N. Burdenko of the Ministry of Health of Russia (Voronezh, Russia)

2. Head of the Department of Organisation of Pharmaceutical Business, Clinical Pharmacy and Pharmacognosy, Voronezh State Medical University named after N.N. Burdenko of the Ministry of Health of Russia (Voronezh, Russia)

3. Department of Medical Biochemistry, Molecular and Cell Biology, Voronezh State University (Voronezh, Russia)

4. Voronezh State Medical University named after N.N. Burdenko of the Ministry of Health of Russia (Voronezh, Russia)

5. Molecular and Cell Biology, Voronezh State University (Voronezh, Russia)

Abstract

Relevance. In many countries plants have long been used in folk medicine as a source of medicines, as they are well tolerated, gradual development of therapeutic effect and a mild effect on the body. Due to these features such medicines are being safely used in the treatment and prevention of exacerbations of chronic diseases: of cardiovascular system, respiratory system, digestive system, pathologies of the urinary tract, etc., and also as a rehabilitation therapy after past diseases. The purpose of the study is to systematize and generalize the data of world literature concerning the general health-improving and tonic properties study of plants growing in the Republic of Buryatia. Material and methods. In this work used publication materials from the PubMed and е-library databases, search.rsl. The keyword search: restorative, tonic effect, herbal medicines, medicinal plants of Buryatia, biologically active substances, Astragalus membranaceus, Saposhnikovia divaricatа, Scutellaria baicalensis, Sedum roseum, Crataegus sangunea. The survey comprises the data of foreign and national articles, published on the topic during last 20 years. Conclusions. All the plants listed in this review are used for thousands of years in the Tibetan medicine. Based on the analysis of the presented literature data, their range of medicinal use is much wider, then the applications in modern clinical practice. The information reported in this review may be the basis for the development of new herbal medicines, including officinal mixture, with specified pharmacological properties.

Publisher

Russian Vrach, Publishing House Ltd.

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