SECONDARY METABOLITES OF CUSCUTA CAMPESTRIS YUNCK

Author:

Adzhiakhmetova S.L.1ORCID,Pozdnyakov D.I.1ORCID,Dibizheva N.M.1ORCID,Oganesyan E.T.1ORCID

Affiliation:

1. Pyatigorsk Medical-Pharmaceutical Institute – branch Volgograd State Medical University; 11 Kalinina Ave., Pyatigorsk, 357532, Russian Federastion

Abstract

Introduction. In the North Caucasus Cuscuta campestris Yunck. is widespread, which parasitizes crops, vegetable gardens, and flower beds. The main classes of biologically active substances of parasites of the genus Cuscuta L. are polyphenolic compounds. The purpose of this work was to study some secondary metabolites of C. campestris stems collected from different host plants. Material and methods. Objects of study: stems of C. campestris collected in the village. Novkus-Artesian of the Neftekumsky district of the Stavro-pol Territory with Alhagi pseudalhagi (M.Bieb.) Desv., Beta vulgaris L., Leucanthemum vulgare Lam. The determination of the total content of antioxi-dants in the analyzed extracts was carried out using a TsvetYauza-01-AA device with amperometric detection. Determination of the total content of phenolic compounds using the Folin-Ciocalteu reagent was carried out by the spectrophotometric method on an SF-102 spectrophotometer. Results. In the extracts studied, the Shinoda test using magnesium showed a red color due to the formation of anthocyanidins, and a yellow-green color due to the reaction with iron (III) salts. The maximum content of the sum of phenolic compounds and the sum of flavonoids is observed in the extract from the stems of C. campestris, collected from A. pseudalhagi, during extraction with 70% ethyl alcohol and amounts to 10,18±0,47% and 5,71±0,25%, respectively. When determining the total content of antioxidants, the optimal extractant is purified water: the maximum content in the aqueous extract obtained from the stems of C. campestris collected from A. pseudalhagi is, in terms of quercetin and gallic acid, 2,02±0,08 mg/g, 1,31±0,05 mg/g, respectively. Conclusions. In the analyzed extracts, patterns were revealed between the nature of the extractant, the total content of polyphenolic compounds and host plants. It was found that the extracts obtained by extraction with 70% ethyl alcohol from the stems of C. campestris collected from A. pseudalhagi exhibited the maximum total content of polyphenolic compounds and flavonoids. Comparable results were obtained when determining the total content of antioxidants and flavonoids in extracts from the stems of C. campestris collected from B. vulgaris and L. vulgare

Publisher

Russian Vrach, Publishing House Ltd.

Reference21 articles.

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3. (In Russ.).

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