Affiliation:
1. Tver State Medical University, Ministry of Health of Russia
Abstract
The possibilities of ursodeoxycholic acid (UDCA) application in clinical practice are evaluated. Statistical analysis of data from modern Russian and foreign literature sources, as well as recent scientific works in the field of pharmacology of UDCA was carried out. UDCA has a significant potential, as it can affect both the body as a whole and its individual organs, systems and processes. This effect is realized either by immunomodulating properties of the acid or directly on the cells themselves through bile acid receptors (bile acids together with UDCA are able to perform the role of signaling molecules). It should be noted that in many studies antagonism of UDCA and other bile acids was observed.
Publisher
Russian Vrach, Publishing House Ltd.