RELATIONSHIP OF VITAMIN D LEVEL WITH SOME BIOCHEMICAL INDICATORS OF BLOOD IN PATIENTS OVER 60 YEARS OF AGE WITH OSTEOARTHRITIS BEFORE SURGERY AND AFTER PROSTHETICS

Abstract

Objective. To study the relationship between vitamin D level and biochemical blood parameters in patients over 60 years of age with osteoarthritis (OA). Material and methods. In the investigation 200 patients aged 60–80 years (mean age – 69,03±2,34 years; 170 [85%] women and 30 [15%] men) with OA being observed in the out-patient medical institutions of Murmansk including 100 patients after total joint replacement took part. Vitamin D, triglycerides, thyroid stimulating hormone (TSH), total cholesterol, low and high density lipoproteins, blood glucose, uric acid, creatinine, total protein, and blood calcium levels were determined in all patients. Results. Vitamin D deficiency was more frequently observed in the group of patients who did not receive surgical treatment compared to patients who underwent arthroplasty. A statistically significant relationship between vitamin D level and blood glucose was detected in the group of non-prosthetic patients. The relationship between vitamin D level, albumin and TSH was revealed in the group of prosthetic patients.