LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS-Reference-Cited by-同舟云学术

LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS

Published:2017-06-28 Issue:3 Volume:12 Page:73-80
ISSN:2410-6593
Container-title:Fine Chemical Technologies
language:
Short-container-title:Fine Chem. Tech.

Author:

Burlyaev V. V.¹,Davydenko А.¹,Kornyushko V. F.¹,Russu L. I.²,Mezentseva M.²

Affiliation:

1. Moscow Technological University (Institute of Fine Chemical Technologies)

2. N.F. Gamaleya Federal Research Center of Epidemiology and Microbiology of the Ministry of Health of the Russian Federation

Abstract

The paper deals with laboratory preclinical studies of the impact of targeted anticancer drugs on the life of A-549 cell cultures of the cancer origin (lung carcinoma). Preclinical studies enable evaluating the effectiveness of targeted therapy drugs, possible contraindications and side effects in order to determine in future the scope of clinical trials and the possibility of performing them. It is proposed to develop information support of preclinical research. In this work the use of functional modeling technology for building a logic-information model in the category of IDEF0 is considered. For detailed elaboration of the model it is necessary to review step-by-step the whole research process. The necessity of creating the information support is connected to the tasks of structuring, storage and processing large amounts of experimental data.

Publisher

RTU MIREA

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