Impact of <i>CYP2D6*10</i> polymorphism on the pharmacokinetics of mirtazapine and its desmethylated metabolite in Japanese psychiatric patients treated with mirtazapine-Reference-Cited by-同舟云学术

Impact of CYP2D6*10 polymorphism on the pharmacokinetics of mirtazapine and its desmethylated metabolite in Japanese psychiatric patients treated with mirtazapine

Published:2015 Issue:0 Volume:6 Page:5-15
ISSN:1884-8826
Container-title:Clinical Neuropsychopharmacology and Therapeutics
language:en
Short-container-title:CNPT

Author:

Watanabe Takashi¹,Hayashi Yuki¹,Aoki Akiko¹,Ishiguro Shin¹,Ueda Mikito¹,Akiyama Kazufumi²,Kato Kazuko³,Inoue Yoshimasa¹,Tsuchimine Shoko⁴,Yasui-Furukori Norio⁴,Shimoda Kazutaka¹

Affiliation:

1. Department of Psychiatry, Dokkyo Medical University School of Medicine

2. Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine

3. Sakura La Mental Clinic

4. Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine

Publisher

The Japanese Society of Clinical Neuropsychopharmacology

Subject

Pharmacology (medical),Psychiatry and Mental health,Clinical Neurology

Reference39 articles.

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3. [3] De Boer T, Nefkens F, Van Helvoirt A. The alpha 2-adrenoceptor antagonist Org 3770 enhances serotonin transmission in vivo. Eur J Pharmacol 1994; 253(1-2): R5-6.

4. [4] De Boer TH, Nefkens F, van Helvoirt A, van Delft AM. Differences in modulation of noradrenergic and serotonergic transmission by the alpha-2 adrenoceptor antagonists, mirtazapine, mianserin and idazoxan. J Pharmacol Exp Ther 1996; 277(2): 852-860.

5. [5] Thompson C. Mirtazapine versus selective serotonin reuptake inhibitors. J Clin Psychiatry 1999; 60 Suppl 17: 18-22; discussion 46-18.

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